000216592 001__ 216592
000216592 005__ 20181203024154.0
000216592 0247_ $$2doi$$a10.1249/Mss.0000000000000726
000216592 022__ $$a0195-9131
000216592 02470 $$2ISI$$a000364561800016
000216592 037__ $$aARTICLE
000216592 245__ $$aNeural Correlates of Clinical Scores in Patients with Anterior Shoulder Apprehension
000216592 260__ $$bAmerican College of Sports Medicine$$c2015$$aPhiladelphia
000216592 269__ $$a2015
000216592 300__ $$a9
000216592 336__ $$aJournal Articles
000216592 520__ $$aIntroduction Anterior shoulder apprehension is a commonly reported complaint in anterior shoulder instability, which may lead to patient morbidity and impede shoulder function. It is the result of a cognitively complex mechanism, which includes anxiety, salience, fear, and anticipation. Purpose The aim of this prospective case-control study was to correlate five clinically established scores using functional magnetic resonance imaging to assess brain activation patterns in patients with apprehension related to anterior shoulder instability. Methods This study includes 28 consecutive male right-handed patients ( mean +/- SEM, 26.8 +/- 1.2 yr) with positive shoulder apprehension test and 10 healthy matched control participants without apprehension or a history of instability. Task- related and functional connectivity functional magnetic resonance imaging activation patterns occurring during apprehension video cue stimulation were correlated with five clinical tests and scores: Visual Analog Scale ( VAS), Rowe score for instability, Simple Shoulder Test, Subjective Shoulder Value ( SSV), and Western Ontario Shoulder Instability ( WOSI). Results Rowe, pain VAS, and WOSI scores correlated with prefrontal cortex, dorsolateral prefrontal cortex, dorsomedial prefrontal cortex, somatosensory area, and parieto-occipital and temporal areas (default mode network). Rowe score additionally correlated with frontal pole, anterior midcingulate cortex, and visual areas. Moreover, SSV correlated with task-related brain activity in the bilateral precentral gyrus, bilateral postcentral gyrus, and bilateral superior parietal lobe. Conclusions Overall, Rowe score provides the strongest link between shoulder apprehension and brain level alterations as it correlates with the highest number of independent components involving areas responsible for both motor and cognitive functions, whereas pain VAS and WOSI occupy an intermediately strong link recruiting less brain networks. Finally, Simple Shoulder Test and SSV have the weakest link at the brain level.
000216592 6531_ $$aSPORTS MEDICINE
000216592 6531_ $$aINSTABILITY
000216592 6531_ $$aFMRI
000216592 6531_ $$aNEUROIMAGERY
000216592 700__ $$uUniv Hosp Geneva, Dept Surg, Div Orthoped & Trauma Surg, Geneva, Switzerland$$aCunningham, Gregory
000216592 700__ $$uUniv Hosp Geneva, Dept Imaging & Med Informat, Geneva, Switzerland$$aZanchi, Davide
000216592 700__ $$uUniv Hosp Geneva, Dept Imaging & Med Informat, Geneva, Switzerland$$aEmmert, Kirsten
000216592 700__ $$0246540$$g224789$$uUniv Hosp Geneva, Dept Imaging & Med Informat, Geneva, Switzerland$$aKopel, Rotem
000216592 700__ $$0240173$$g152027$$uUniv Hosp Geneva, Dept Imaging & Med Informat, Geneva, Switzerland$$aVan De Ville, Dimitri
000216592 700__ $$uUniv Hosp Geneva, Dept Surg, Div Orthoped & Trauma Surg, Geneva, Switzerland$$aLaedermann, Alexandre
000216592 700__ $$uUniv Geneva, Fac Med, CH-1227 Geneva, Switzerland$$aHaller, Sven
000216592 700__ $$aHoffmeyer, Pierre$$uUniv Hosp Geneva, Dept Surg, Div Orthoped & Trauma Surg, Geneva, Switzerland
000216592 773__ $$j47$$tMedicine And Science In Sports And Exercise$$k12$$q2612-2620
000216592 909C0 $$xU12143$$0252169$$pMIPLAB
000216592 909CO $$pSTI$$particle$$ooai:infoscience.tind.io:216592
000216592 917Z8 $$x152027
000216592 937__ $$aEPFL-ARTICLE-216592
000216592 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000216592 980__ $$aARTICLE