000216436 001__ 216436
000216436 005__ 20180913063600.0
000216436 0247_ $$2doi$$a10.1364/Oe.23.032158
000216436 022__ $$a1094-4087
000216436 02470 $$2ISI$$a000366687200052
000216436 037__ $$aARTICLE
000216436 245__ $$aTwo-photon imaging through a multimode fiber
000216436 260__ $$aWashington$$bOptical Soc Amer$$c2015
000216436 269__ $$a2015
000216436 300__ $$a13
000216436 336__ $$aJournal Articles
000216436 520__ $$aIn this work we demonstrate 3D imaging using two-photon excitation through a 20 cm long multimode optical fiber (MMF) of 350 mu m diameter. The imaging principle is similar to single photon fluorescence through a MMF, except that a focused femtosecond pulse is delivered and scanned over the sample. In our approach, focusing and scanning through the fiber is accomplished by digital phase conjugation using mode selection by time gating with an ultra-fast reference pulse. The excited two-photon emission is collected through the same fiber. We demonstrate depth sectioning by scanning the focused pulse in a 3D volume over a sample consisting of fluorescent beads suspended in a polymer. The achieved resolution is 1 mu m laterally and 15 mu m axially. Scanning is performed over an 80x80 mu m field of view. To our knowledge, this is the first demonstration of high-resolution three-dimensional imaging using two-photon fluorescence through a multimode fiber. (C) 2015 Optical Society of America
000216436 700__ $$aMorales-Delgado, Edgar E.$$uEcole Polytech Fed Lausanne, Sch Engn, Lab Appl Photon Devices, CH-1015 Lausanne, Switzerland
000216436 700__ $$0244715$$aPsaltis, Demetri$$g174684
000216436 700__ $$0243489$$aMoser, Christophe$$g199130$$uEcole Polytech Fed Lausanne, Sch Engn, Lab Appl Photon Devices, CH-1015 Lausanne, Switzerland
000216436 773__ $$j23$$k25$$q32158-32170$$tOptics Express
000216436 909C0 $$0252211$$pLAPD$$xU12209
000216436 909C0 $$0252333$$pLO$$xU11723
000216436 909CO $$ooai:infoscience.tind.io:216436$$pSTI$$particle
000216436 917Z8 $$x199130
000216436 937__ $$aEPFL-ARTICLE-216436
000216436 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000216436 980__ $$aARTICLE