From Dimethylamine to Pyrrolidine: The Development of an Improved Nickel Pincer Complex for Cross-Coupling of Nonactivated Secondary Alkyl Halides
Perez Garcia, Pablo M.; Di Franco, Thomas; Epenoy, Alexandre; Scopelliti, Rosario; Hu, Xile
2016
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Abstract

Replacement of a dimethyl amino group of the amidobis(amine) nickel(II) pincer complex (1), [((N2N)-N-Me)-Ni-Cl], by a pyrrolidino group resulted in a new nickel(II) pincer complex (2), [((PNNN)-N-yr-N-Me)Ni-Cl]. Complex 2 is an efficient catalyst for Kumada and Suzuki-Miyaura cross-coupling of nonactivated secondary alkyl halides, while complex 1 is largely inactive. The significant activity difference is tentatively attributed to a minimal structural difference, which leads to a more hemilabile ligand.

Details

Title From Dimethylamine to Pyrrolidine: The Development of an Improved Nickel Pincer Complex for Cross-Coupling of Nonactivated Secondary Alkyl Halides
Author(s) Perez Garcia, Pablo M. ; Di Franco, Thomas ; Epenoy, Alexandre ; Scopelliti, Rosario ; Hu, Xile
Published in ACS Catalysis
Pagination 4
Volume 6
Issue 1
Pages 258-261
Date 2016
Publisher Washington, American Chemical Society
ISSN 2155-5435
Keywords
DOI https://doi.org/10.1021/acscatal.5b02324
Other identifier(s) View record in Web of Science
Laboratories LSCI
Record Appears in Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LSCI - Laboratory of Inorganic Synthesis and Catalysis
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2016-01-22

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