000213744 001__ 213744
000213744 005__ 20190317000330.0
000213744 0247_ $$2doi$$a10.1039/C5NR06157A
000213744 02470 $$2ISI$$a000369591400016
000213744 037__ $$aARTICLE
000213744 245__ $$aAntibacterial Au nanostructured surfaces
000213744 269__ $$a2016
000213744 260__ $$bRoyal Soc Chemistry$$c2016$$aCambridge
000213744 300__ $$a6
000213744 336__ $$aJournal Articles
000213744 520__ $$aWe present here a technological platform for engineering Au nanotopographies by templated electrodeposition for antibacterial surfaces. Three different types of nanostructures were fabricated: nanopillars, nanorings and nanonuggets. The nanopillars are the basic structures and are 50 nm in diameter and 100 nm in height. Particular arrangement of the nanopillars in various geometries formed nanorings and nanonuggets. Flat surfaces, rough substrate surfaces, and various nanostructured surfaces were compared for their abilities to attach and kill bacterial cells. Methicillin-resistant Staphylococcus aureus, a Gram-positive bacterial strain responsible for many infections in health care system, was used as the model bacterial strain. It was found that all the Au nanostructures, regardless their shapes, exhibited similarly excellent antibacterial property. The comparison of live cells attached to nanotopographic surfaces showed that the number of live S. aureus cells was < 1 % of that from flat and rough reference surfaces. Our micro/nanofabrication process is a scalable approach based on cost-efficient selforganization and provides potential for further developing functional surfaces to study the behavior of microbes on nanoscale topographies.
000213744 700__ $$0245976$$g201009$$aWu, Songmei
000213744 700__ $$aZuber, Flavia
000213744 700__ $$0240120$$g145781$$aBrugger, Jürgen
000213744 700__ $$aManiura-Weber, Katharina
000213744 700__ $$aRen, Qun
000213744 773__ $$j8$$tNanoscale$$k5$$q2620-2625
000213744 8564_ $$uhttps://infoscience.epfl.ch/record/213744/files/C5NR06157A.pdf$$zPublisher's version$$s1403129$$yPublisher's version
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000213744 917Z8 $$x229906
000213744 917Z8 $$x229906
000213744 937__ $$aEPFL-ARTICLE-213744
000213744 973__ $$rNON-REVIEWED$$sPUBLISHED$$aOTHER
000213744 980__ $$aARTICLE