Cross-Coupling of Nonactivated Primary and Secondary Alkyl Halides with Aryl Grignard Reagents Catalyzed by Chiral Iron Pincer Complexes

Iron(III) bisoxazolinylphenylamido (bopa) pincer complexes are efficient precatalysts for the cross-coupling of nonactivated primary and secondary alkyl halides with phenyl Grignard reagents. The reactions proceed at room temperature in moderate to excellent yields. A variety of functional groups can be tolerated. The enantioselectivity of the coupling of secondary alkyl halides is low.


Published in:
Synthesis-Stuttgart, 47, 12, 1726-1732
Year:
2015
Publisher:
Stuttgart, Georg Thieme Verlag
ISSN:
0039-7881
Keywords:
Laboratories:




 Record created 2015-09-28, last modified 2018-03-17


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