In this issue of Neuron, Manita et al. (2015) report that reciprocal excitatory interactions between higher-order frontal motor cortex and primary sensorimotor cortex might play a key role in hindlimb sensory perception in mice. In this issue of Neuron, Manita et al. report that reciprocal excitatory interactions between higher order frontal motor cortex and primary sensorimotor cortex might play a key role in hindlimb sensory perception in mice. © 2015 Elsevier Inc.