Erythrocyte-binding therapeutics
2013
Abstract
Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired. Fusions with targeting peptides direct the fusions to the target, for instance a tumor, where the erythrocyte-binding ligands reduce or entirely eliminate blood flow to the tumor by recruiting erythrocytes to the target.
Details
Title
Erythrocyte-binding therapeutics
Author(s)
Hubbel, Jeffrey ; Kontos, Stephane ; Dane, Karen ; Hubbell, Jeffrey
Date
2013
Keywords
Note
Alternative title(s) :
(de) Erythrozytenbindende therapeutika
(fr) Agents thérapeutiques se liant aux érythrocytes
Other identifier(s)
EPO Family ID: 48326347
EPO Family ID: 45564995
EPO Family ID: 46455557
EPO Family ID: 51985354
EPO Family ID: 45564995
EPO Family ID: 46455557
EPO Family ID: 51985354
Patent number(s)
US11884721 (B2)
JP2022184955 (A)
NZ722352 (A)
US2022125945 (A1)
US11246943 (B2)
US2021238277 (A1)
CA2807942 (C)
AU2019257362 (B2)
US2021079077 (A1)
US10919963 (B2)
US10800838 (B2)
JP2020147591 (A)
ES2781773 (T3)
EA035931 (B1)
JP6716619 (B2)
JP6692602 (B2)
IL234056 (B)
US2020101169 (A1)
JP6648184 (B2)
EP2814500 (B1)
US2019382479 (A1)
AU2019257362 (A1)
US10471155 (B2)
AU2017276218 (B2)
HK1256601 (A1)
HK1256421 (A1)
US10392437 (B2)
CN110075283 (A)
CN110075284 (A)
AU2017200830 (B2)
US10265415 (B2)
US10265416 (B2)
JP2018135348 (A)
JP2018127458 (A)
US2018185505 (A1)
US2018185507 (A1)
US2018185508 (A1)
JP6348146 (B2)
CN108129554 (A)
CN108117586 (A)
US2018100011 (A1)
US9901645 (B2)
US9901646 (B2)
CN103282380 (B)
US9878048 (B2)
AU2017276218 (A1)
BR112014020304 (A8)
US9850296 (B2)
US9814780 (B2)
EA028087 (B1)
AU2013220079 (B2)
EA201790862 (A1)
BR112014020304 (A2)
NZ628851 (A)
US2017066825 (A1)
AU2017200830 (A1)
JP2017008046 (A)
SG10201609500Q (A)
US2016361431 (A1)
US9518087 (B2)
US9517257 (B2)
US2016354484 (A1)
US2016354453 (A1)
US2016354454 (A1)
AU2011289579 (B2)
JP6017422 (B2)
HK1202051 (A1)
MX2014009900 (A)
JP2015508770 (A)
KR20150010699 (A)
CN104271148 (A)
EA201491524 (A1)
EP2814500 (A1)
US2014356384 (A1)
SG11201404943P (A)
AU2013220079 (A1)
EP2603520 (A4)
JP2013541504 (A)
CN103282380 (A)
CA2864432 (A1)
WO2013121296 (A1)
EP2603520 (A2)
WO2012021512 (A8)
AU2011289579 (A1)
US2012178139 (A1)
WO2012021512 (A3)
CA2807942 (A1)
US2012039989 (A1)
WO2012021512 (A2)
JP2022184955 (A)
NZ722352 (A)
US2022125945 (A1)
US11246943 (B2)
US2021238277 (A1)
CA2807942 (C)
AU2019257362 (B2)
US2021079077 (A1)
US10919963 (B2)
US10800838 (B2)
JP2020147591 (A)
ES2781773 (T3)
EA035931 (B1)
JP6716619 (B2)
JP6692602 (B2)
IL234056 (B)
US2020101169 (A1)
JP6648184 (B2)
EP2814500 (B1)
US2019382479 (A1)
AU2019257362 (A1)
US10471155 (B2)
AU2017276218 (B2)
HK1256601 (A1)
HK1256421 (A1)
US10392437 (B2)
CN110075283 (A)
CN110075284 (A)
AU2017200830 (B2)
US10265415 (B2)
US10265416 (B2)
JP2018135348 (A)
JP2018127458 (A)
US2018185505 (A1)
US2018185507 (A1)
US2018185508 (A1)
JP6348146 (B2)
CN108129554 (A)
CN108117586 (A)
US2018100011 (A1)
US9901645 (B2)
US9901646 (B2)
CN103282380 (B)
US9878048 (B2)
AU2017276218 (A1)
BR112014020304 (A8)
US9850296 (B2)
US9814780 (B2)
EA028087 (B1)
AU2013220079 (B2)
EA201790862 (A1)
BR112014020304 (A2)
NZ628851 (A)
US2017066825 (A1)
AU2017200830 (A1)
JP2017008046 (A)
SG10201609500Q (A)
US2016361431 (A1)
US9518087 (B2)
US9517257 (B2)
US2016354484 (A1)
US2016354453 (A1)
US2016354454 (A1)
AU2011289579 (B2)
JP6017422 (B2)
HK1202051 (A1)
MX2014009900 (A)
JP2015508770 (A)
KR20150010699 (A)
CN104271148 (A)
EA201491524 (A1)
EP2814500 (A1)
US2014356384 (A1)
SG11201404943P (A)
AU2013220079 (A1)
EP2603520 (A4)
JP2013541504 (A)
CN103282380 (A)
CA2864432 (A1)
WO2013121296 (A1)
EP2603520 (A2)
WO2012021512 (A8)
AU2011289579 (A1)
US2012178139 (A1)
WO2012021512 (A3)
CA2807942 (A1)
US2012039989 (A1)
WO2012021512 (A2)
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LMRP - Regenerative Medicine and Pharmacobiology Laboratory
Scientific production and competences > SV - School of Life Sciences > SV Archives > LMRP - Regenerative Medicine and Pharmacobiology Laboratory
Scientific production and competences > Non-academic units > TTO - Technology Transfer Office
Work produced at EPFL
Patents
Scientific production and competences > SV - School of Life Sciences > SV Archives > LMRP - Regenerative Medicine and Pharmacobiology Laboratory
Scientific production and competences > Non-academic units > TTO - Technology Transfer Office
Work produced at EPFL
Patents
Record creation date
2015-09-22