Process and reactor for the manufacture of powders of inhalable medicaments

The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor(a) a segmented flow of that fluid comprised of discrete volumes or(b) a fluid mixture being separated by discrete volumes of a separating fluid which is substantially immiscible with said fluid,characterized in that the crystallization is initiated by application of ultrasound.


    Record created on 2015-09-22, modified on 2016-08-09


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