Cell Seeding is a key factor for good regeneration in tissue engineering. In order to ensure uniform tissue regeneration, a system has to be found to distribute cells evenly within the scaffold that will carry them in the body. In this extent, this work try to find an accurate description of compression forced induced suction which is a seeding technique with reported satisfying seeding efficiency. This description will take the form of a numerical model with COMSOL Multiphysics and will allow us to maximize the seeding in terms of homogeneity. In order to find the best possible seeding, strains and velocities of the compression will be further analyzed. The scaffold material properties will also be examined in order to have the best possible material for that kind of applications.