Cancer metastasis: Perivascular macrophages under watch

TIE2-expressing macrophages cluster around blood vessels and sustain tumor angiogenesis. Harney and colleagues now use live imaging of mouse mammary tumors to show that these perivascular macrophages also promote the transient opening of tumor blood vessels to facilitate hematogenous cancer cell dissemination and metastasis.


Published in:
Cancer Discovery, 5, 9, 906–908
Year:
2015
Publisher:
Philadelphia, American Association for Cancer Research
ISSN:
2159-8274
Laboratories:




 Record created 2015-08-17, last modified 2018-09-13


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)