Compact imaging system with single-photon sensitivity and picosecond time resolution for fluorescence-guided surgery with lifetime imaging capability

We present a single-photon camera for fluorescence imaging capable of providing both intensity and images, with an accuracy better than 100ps; the camera was fabricated in standard CMOS technology. As a first step towards the study of biologically relevant samples, it was used to characterize in-vitro cultured melanoma cells labeled with indocyanine green (ICG) and ICG conjugated with cyclic pentapeptide (RGDfK). The application field would be fluorescence-guided surgical oncology.© 2013 OSA-SPIE.


Published in:
CLINICAL AND BIOMEDICAL SPECTROSCOPY AND IMAGING III, 8798
Year:
2013
Publisher:
International Society for Optical Engineering
ISSN:
0277-786X
Keywords:
Laboratories:




 Record created 2015-07-31, last modified 2018-09-13


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