Triggered Release from Liposomes through Magnetic Actuation of Iron Oxide Nanoparticle Containing Membranes

The ideal nanoscale drug delivery vehicle allows control over the released dose in space and time. We demonstrate that this can be achieved by stealth liposomes comprising self-assembled superparamagnetic iron oxide nanoparticles (NPs) individually stabilized with palmityl-nitroDOPA incorporated in the lipid membrane. Alternating magnetic fields were used to control timing and dose of repeatedly released cargo from such vesicles by locally heating the membrane, which changed its permeability without major effects on the environment. © 2011 American Chemical Society.


Published in:
Nano Letters, 11, 1664-1670
Year:
2011
Publisher:
American Chemical Society
ISSN:
1530-6984
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2015-04-09, last modified 2018-10-01

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