000206345 001__ 206345
000206345 005__ 20181203023815.0
000206345 0247_ $$2doi$$a10.1039/c2cp23357f
000206345 022__ $$a1463-9084
000206345 037__ $$aARTICLE
000206345 245__ $$aCoherent manipulation of free amino acids fluorescence
000206345 260__ $$c2012
000206345 269__ $$a2012
000206345 336__ $$aJournal Articles
000206345 520__ $$aCoherent manipulation of molecular wavepackets in biomolecules might contribute to the quest towards label-free cellular imaging and protein identification. We report the use of optimally tailored UV laser pulses in pump-probe depletion experiments that selectively enhance or decrease fluorescence between two aromatic amino acids: tryptophan (Trp) and tyrosine (Tyr). Selective fluorescence modulation is achieved with a contrast of ∼35%. A neat modification of the time-dependent fluorescence depletion signal of Trp is observed, while the Tyr transient trace remains unchanged. The mechanism invoked for explaining the change of the depletion of Trp is a less efficient coupling between the fluorescing state and the higher non-radiative excited states by the optimally shaped pulse, than by the reference pulse. © 2012 the Owner Societies.
000206345 700__ $$aRondi, A.
000206345 700__ $$aBonacina, L.
000206345 700__ $$aTrisorio, A.
000206345 700__ $$0244705$$g204280$$aHauri, C.
000206345 700__ $$aWolf, J.-P.
000206345 773__ $$j14$$tPhysical Chemistry Chemical Physics$$k26$$q9317
000206345 909C0 $$xU12312$$0252525$$pGR-HAU
000206345 909C0 $$xU10658$$0252363$$pLPAP
000206345 909CO $$pSB$$particle$$ooai:infoscience.tind.io:206345
000206345 917Z8 $$x204280
000206345 917Z8 $$x249835
000206345 937__ $$aEPFL-ARTICLE-206345
000206345 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000206345 980__ $$aARTICLE