000205505 001__ 205505
000205505 005__ 20190317000120.0
000205505 0247_ $$2doi$$a10.1038/srep07316
000205505 022__ $$a2045-2322
000205505 02470 $$2ISI$$a000346267900004
000205505 037__ $$aARTICLE
000205505 245__ $$aSmall effects of smoking on visual spatiotemporal processing
000205505 269__ $$a2014
000205505 260__ $$bNature Publishing Group$$c2014$$aLondon
000205505 300__ $$a6
000205505 336__ $$aJournal Articles
000205505 520__ $$aNicotine is an important stimulant that is involved in modulating many neuronal processes, including those related to vision. Nicotine is also thought to play a key role in schizophrenia: A genetic variation of the cholinergic nicotine receptor gene, alpha-7 subunit (CHRNA7) has been shown to be associated with stronger backward masking deficits in schizophrenic patients. In this study, we tested visual backward masking in healthy smokers and non-smokers to further understand the effects of nicotine on spatiotemporal vision. In the first study, we tested 48 participants, a group of non-smokers (n=12) and three groups of regular smokers that were either nicotine deprived (n=12), non-deprived (n=12) or deprived but were allowed to smoke a cigarette directly before the start of the experiment (n=12). Performance was similar across groups, except for some small negative effects in nicotine-deprived participants. In the second study, we compared backward masking performance between regular smokers and non-smokers for older (n=37, 13 smokers) and younger (n=67, 21 smokers) adults. Older adults performed generally worse than younger adults but there were no significant differences in performance between smokers and non-smokers. Taken together, these findings indicate that nicotine has no long-term negative effects on visual spatiotemporal processing as determined by visual backward masking.
000205505 700__ $$uAgr Univ Georgia, Inst Cognit Neurosci, Tbilisi, Rep of Georgia$$aKunchulia, Marina
000205505 700__ $$uUniv Aberdeen, Sch Psychol, Aberdeen AB9 1FX, Scotland$$aPilz, Karin S.
000205505 700__ $$g164642$$aHerzog, Michael H.$$0243629
000205505 773__ $$j4$$tScientific Reports$$q7316
000205505 8564_ $$uhttps://infoscience.epfl.ch/record/205505/files/srep07316.pdf$$zPublisher's version$$s506446$$yPublisher's version
000205505 909C0 $$xU10987$$0252249$$pLPSY
000205505 909CO $$qGLOBAL_SET$$pSV$$ooai:infoscience.tind.io:205505$$particle
000205505 917Z8 $$x166039
000205505 917Z8 $$x182396
000205505 937__ $$aEPFL-ARTICLE-205505
000205505 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000205505 980__ $$aARTICLE