000204267 001__ 204267
000204267 005__ 20190317000056.0
000204267 022__ $$a0369-3392
000204267 02470 $$2ISI$$a000350770500039
000204267 0247_ $$2doi$$a10.1038/nature14024
000204267 037__ $$aARTICLE
000204267 245__ $$aMechanosensory interactions drive collective behaviour in Drosophila
000204267 269__ $$a2015
000204267 260__ $$aLondon$$bNature Publishing Group$$c2015
000204267 300__ $$a16
000204267 336__ $$aJournal Articles
000204267 520__ $$aCollective behaviour enhances environmental sensing and decision-making in groups of animals. Experimental and theoretical investigations of schooling fish, flocking birds and human crowds have demonstrated that simple interactions between individuals can explain emergent group dynamics. These findings indicate the existence of neural circuits that support distributed behaviours, but the molecular and cellular identities of relevant sensory pathways are unknown. Here we show that Drosophila melanogaster exhibits collective responses to an aversive odour: individual flies weakly avoid the stimulus, but groups show enhanced escape reactions. Using high-resolution behavioural tracking, computational simulations, genetic perturbations, neural silencing and optogenetic activation we demonstrate that this collective odour avoidance arises from cascades of appendage touch interactions between pairs of flies. Inter-fly touch sensing and collective behaviour require the activity of distal leg mechanosensory sensilla neurons and the mechanosensory channel NOMPC. Remarkably, through these inter-fly encounters, wild-type flies can elicit avoidance behaviour in mutant animals that cannot sense the odour-a basic form of communication. Our data highlight the unexpected importance of social context in the sensory responses of a solitary species and open the door to a neural-circuit-level understanding of collective behaviour in animal groups.
000204267 6531_ $$aDrosophila
000204267 6531_ $$aCollective Behavior
000204267 6531_ $$aMechanosensory
000204267 6531_ $$aNeuron
000204267 6531_ $$aEvolutionary Robotics
000204267 700__ $$0245307$$aRamdya, Pavan$$g196838
000204267 700__ $$0243230$$aLichocki, Pawel$$g191506
000204267 700__ $$aCruchet, Steeve
000204267 700__ $$aFrisch, Lukas
000204267 700__ $$aTse, Winnie
000204267 700__ $$0240742$$aFloreano, Dario$$g111729
000204267 700__ $$aBenton, Richard
000204267 773__ $$j519$$q233–236$$tNature
000204267 8564_ $$s3251911$$uhttps://infoscience.epfl.ch/record/204267/files/nature14024.pdf$$yPublisher's version$$zPublisher's version
000204267 909C0 $$0252161$$pLIS$$xU10370
000204267 909CO $$ooai:infoscience.tind.io:204267$$pSTI$$particle$$qGLOBAL_SET
000204267 917Z8 $$x196838
000204267 917Z8 $$x111729
000204267 917Z8 $$x255330
000204267 937__ $$aEPFL-ARTICLE-204267
000204267 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000204267 980__ $$aARTICLE