Transcranial Direct Current Stimulation (tDCS) induces selective modulation of cortical excitability. This technique, as well as Brain–Computer Interfaces (BCIs), has been proposed as a supporting tool for neurorehabilitation. Here we show evidence that tDCS in SCI patients and control subjects modulates spectral features related to motor-imagery, yielding consistent discrimination. This suggests that tDCS can have beneficial effects for BCI-assisted neurorehabilitation.