000202488 001__ 202488
000202488 005__ 20181203023634.0
000202488 0247_ $$2doi$$a10.1093/ilar/ilu002
000202488 022__ $$a1084-2020
000202488 02470 $$2ISI$$a000342218800002
000202488 037__ $$aARTICLE
000202488 245__ $$aSocial Defeat as an Animal Model for Depression
000202488 260__ $$bOxford Univ Press$$c2014$$aOxford
000202488 269__ $$a2014
000202488 300__ $$a12
000202488 336__ $$aJournal Articles
000202488 520__ $$aDepression is one of the most disabling medical conditions in the world today, yet its etiologies remain unclear and current treatments are not wholly effective. Animal models are a powerful tool to investigate possible causes and treatments for human diseases. We describe an animal model of social defeat as a possible model for human depression. We discuss the paradigm, behavioral correlates to depression, and potential underlying neurobiological mechanisms with an eye toward possible future therapies.
000202488 6531_ $$aanimal models
000202488 6531_ $$adepression
000202488 6531_ $$asocial defeat
000202488 6531_ $$astress
000202488 700__ $$0245648$$g213558$$uEcole Polytech Fed Lausanne, Brain Mind Inst, Lausanne, Switzerland$$aHollis, Fiona
000202488 700__ $$aKabbaj, Mohamed
000202488 773__ $$j55$$tIlar Journal$$k2$$q221-232
000202488 909C0 $$xU10454$$0252449$$pBMI
000202488 909CO $$pSV$$particle$$ooai:infoscience.tind.io:202488
000202488 937__ $$aEPFL-ARTICLE-202488
000202488 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000202488 980__ $$aARTICLE