Abstract
The application of macrocycles to previously undruggable targets has aroused a great deal of interest in this structural class. Recent studies advance our understanding of the way macrocycles bind protein targets and provide new strategies and tools to generate peptide-based macrocycles.
Details
Title
Drug discovery: tools and rules for macrocycles
Author(s)
Heinis, Christian
Published in
Nature chemical biology
Pagination
3
Volume
10
Issue
9
Pages
696-8
Date
2014
Publisher
New York, Nature Publishing Group
ISSN
1552-4469
Other identifier(s)
View record in Web of Science
Laboratories
LPPT
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LPPT - Laboratory of Therapeutic Proteins and Peptides
Work produced at EPFL
Journal Articles
Published
Work produced at EPFL
Journal Articles
Published
Record creation date
2014-10-15