Multiciliogenesis: multicilin directs transcriptional activation of centriole formation

During differentiation of multiciliated cells, numerous centrioles are generated in each cell to act as templates for the formation of a corresponding number of cilia. A new study reveals that multicilin, a protein required for multiciliogenesis, is a key component of a regulatory complex that activates the transcription of genes required for centriole formation.


Published in:
Current biology : CB, 24, 16, R746-9
Year:
2014
Publisher:
Cambridge, Cell Press
ISSN:
1879-0445
Laboratories:




 Record created 2014-08-21, last modified 2018-03-17


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