000199270 001__ 199270
000199270 005__ 20180913062523.0
000199270 020__ $$a978-1-4673-1969-0
000199270 022__ $$a1948-3546
000199270 02470 $$2ISI$$a000331259200163
000199270 037__ $$aCONF
000199270 245__ $$aPDMS Microchannel Regenerative Peripheral Nerve Interface
000199270 260__ $$bIeee$$c2013$$aNew York
000199270 269__ $$a2013
000199270 300__ $$a4
000199270 336__ $$aConference Papers
000199270 490__ $$aInternational IEEE EMBS Conference on Neural Engineering
000199270 520__ $$aWe have fabricated a soft silicone structure to support the regeneration of a sciatic nerve. The device consists of 70 parallel (120 x 110 mu m(2)) channels through which axons extend and then reconnect to the muscles on the other side of the device. Through histology and electrophysiology, we show that axons grow through the device and functionality of the muscle control is restored. Nerve functionality as demonstrated with stimulated electromyography (EMG) recordings is still intact at 9 months after implantation. Future work on this device will include electrodes for recording and stimulating the regenerating nerve.
000199270 700__ $$aMusick, Katherine M.
000199270 700__ $$aChew, Daniel J.
000199270 700__ $$aFawcett, James W.
000199270 700__ $$g208625$$aLacour, Stephanie P.$$0246296
000199270 7112_ $$a6th International IEEE EMBS Conference on Neural Engineering (NER)
000199270 773__ $$t2013 6Th International Ieee/Embs Conference On Neural Engineering (Ner)$$q649-652
000199270 909C0 $$xU12393$$0252424$$pLSBI
000199270 909CO $$pconf$$pSTI$$ooai:infoscience.tind.io:199270
000199270 917Z8 $$x208625
000199270 937__ $$aEPFL-CONF-199270
000199270 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000199270 980__ $$aCONF