To embed the diversity and variability of human needs as foundational elements of daylighting design and put human occupants back at the core of the building question, we need to reach out to fundamental discoveries from neuroscience, biology and other fields, which will bring new insights and a deeper understanding of how we interact with our environment. This talk will discuss how to bring exciting research perspectives regarding the assessment of daylighting performance by considering three interpretations of “well-being” in a space: as a human inhabitant of a living space, as a user of a (work)space, and as a witness of a delightful space.