000198626 001__ 198626
000198626 005__ 20181203023503.0
000198626 0247_ $$2doi$$a10.1371/journal.pone.0091620
000198626 022__ $$a1932-6203
000198626 02470 $$2ISI$$a000332839300144
000198626 037__ $$aARTICLE
000198626 245__ $$aComparison of Real-Time Water Proton Spectroscopy and Echo-Planar Imaging Sensitivity to the BOLD Effect at 3 T and at 7 T
000198626 260__ $$bPublic Library of Science$$c2014$$aSan Francisco
000198626 269__ $$a2014
000198626 300__ $$a9
000198626 336__ $$aJournal Articles
000198626 520__ $$aGradient-echo echo-planar imaging (GE EPI) is the most commonly used approach to assess localized blood oxygen level dependent (BOLD) signal changes in real-time. Alternatively, real-time spin-echo single-voxel spectroscopy (SE SVS) has recently been introduced for spatially specific BOLD neurofeedback at 3 T and at 7 T. However, currently it is not known how neurofeedback based on real-time SE SVS compares to real-time GE EPI-based. We therefore compared both methods at high (3 T) and at ultra-high (7 T) magnetic field strengths. We evaluated standard quality measures of both methods for signals originating from the motor cortex, the visual cortex, and for a neurofeedback condition. At 3 T, the data quality of the real-time SE SVS and GE EPI R2* estimates were comparable. At 7 T, the data quality of the real-time GE EPI acquisitions was superior compared to those of the real-time SE SVS. Despite the somehow lower data quality of real-time SE SVS compared to GE EPI at 7 T, SE SVS acquisitions might still be an interesting alternative. Real-time SE SVS allows for a direct and subject-specific T2* estimation and thus for a physiologically more plausible neurofeedback signal.
000198626 700__ $$0249253$$g223415$$uUniv Geneva, Dept Radiol & Med Informat, Geneva, Switzerland$$aKoush, Yury
000198626 700__ $$uUniv Penn, Dept Radiol, CMROI, Philadelphia, PA 19104 USA$$aElliott, Mark A.
000198626 700__ $$uUniv Geneva, Dept Radiol & Med Informat, Geneva, Switzerland$$aScharnowski, Frank
000198626 700__ $$aMathiak, Klaus$$uRhein Westfal TH Aachen, Dept Psychiat Psychotherapy & Psychosomat, Aachen, Germany
000198626 773__ $$j9$$tPlos One$$k3
000198626 909C0 $$xU12143$$0252169$$pMIPLAB
000198626 909CO $$pSTI$$particle$$ooai:infoscience.tind.io:198626
000198626 917Z8 $$x152027
000198626 937__ $$aEPFL-ARTICLE-198626
000198626 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000198626 980__ $$aARTICLE