000198548 001__ 198548
000198548 005__ 20181203023501.0
000198548 0247_ $$2doi$$a10.1039/c3an01836a
000198548 022__ $$a0003-2654
000198548 02470 $$2ISI$$a000333081800008
000198548 037__ $$aARTICLE
000198548 245__ $$aA hydrodynamically optimized nano-electrospray ionization source and vacuum interface
000198548 260__ $$bRoyal Soc Chemistry$$c2014$$aCambridge
000198548 269__ $$a2014
000198548 300__ $$a12
000198548 336__ $$aJournal Articles
000198548 520__ $$aThe coupling of atmospheric pressure ionization (API) sources like electrospray ionization (ESI) to vacuum based applications like mass spectrometry (MS) or ion beam deposition (IBD) is done by differential pumping, starting with a capillary or pinhole inlet. Because of its low ion transfer efficiency the inlet represents a major bottleneck for these applications. Here we present a nano-ESI vacuum interface optimized to exploit the hydrodynamic drag of the background gas for collimation and the reduction of space charge repulsion. Up to a space charge limit of 40 nA we observe 100% current transmission through a capillary with an inlet and show by MS and IBD experiments that the transmitted ion beams are well defined and free of additional contamination compared to a conventional interface. Based on computational fluid dynamics modelling and ion transport simulations, we show how the specific shape enhances the collimation of the ion cloud. Mass selected ion currents in the nanoampere range available further downstream in high vacuum open many perspectives for the efficient use of electrospray ion beam deposition (ES-IBD) as a surface coating method.
000198548 700__ $$uMax Planck Inst Solid State Res, D-70567 Stuttgart, Germany$$aPauly, M.
000198548 700__ $$uTech Univ Berlin, D-01300 Berlin, Germany$$aSroka, M.
000198548 700__ $$uTech Univ Berlin, D-01300 Berlin, Germany$$aReiss, J.
000198548 700__ $$uMax Planck Inst Solid State Res, D-70567 Stuttgart, Germany$$aRinke, G.
000198548 700__ $$uMax Planck Inst Solid State Res, D-70567 Stuttgart, Germany$$aAlbarghash, A.
000198548 700__ $$uMax Planck Inst Solid State Res, D-70567 Stuttgart, Germany$$aVogelgesang, R.
000198548 700__ $$uTech Univ Munich, Chair Prote & Bioanalyt, D-85354 Freising Weihenstephan, Germany$$aHahne, H.
000198548 700__ $$uTech Univ Munich, Chair Prote & Bioanalyt, D-85354 Freising Weihenstephan, Germany$$aKuster, B.
000198548 700__ $$uTech Univ Berlin, D-01300 Berlin, Germany$$aSesterhenn, J.
000198548 700__ $$0240038$$g105546$$uMax Planck Inst Solid State Res, D-70567 Stuttgart, Germany$$aKern, K.
000198548 700__ $$uMax Planck Inst Solid State Res, D-70567 Stuttgart, Germany$$aRauschenbach, S.
000198548 773__ $$j139$$tAnalyst$$k8$$q1856-1867
000198548 909C0 $$xU10152$$0252366$$pLSEN
000198548 909CO $$pSB$$particle$$ooai:infoscience.tind.io:198548
000198548 937__ $$aEPFL-ARTICLE-198548
000198548 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000198548 980__ $$aARTICLE