NIS-Assisted Aza-Friedel-Crafts Reaction with α-Carbamoysulfides as Precursors of

A general and practical N-iodosuccinimide (NIS)-promoted aza-Friedel–Crafts reaction of various aromatic nucleophiles with N-acylimines generated in situ from a-amidosulfides to give a rapid access to highly functionalized amines is described. The newly developed methodology is very mild, fast, efficient, and complementary.


Published in:
Chemistry - A European Journal, 20, 13, 3621-3625
Year:
2014
Publisher:
Weinheim, Wiley-Blackwell
ISSN:
0947-6539
Keywords:
Laboratories:




 Record created 2014-03-15, last modified 2018-03-17


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)