000197243 001__ 197243
000197243 005__ 20190316235846.0
000197243 0247_ $$2doi$$a10.1002/mrm.25171
000197243 022__ $$a0740-3194
000197243 02470 $$2ISI$$a000348139500050
000197243 037__ $$aARTICLE
000197243 245__ $$aA double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T
000197243 260__ $$bWiley-Blackwell$$c2015$$aHoboken
000197243 269__ $$a2015
000197243 300__ $$a7
000197243 336__ $$aJournal Articles
000197243 520__ $$aPurpose Carbon-13 magnetic resonance spectroscopy (13C-MRS) is challenging because of the inherent low sensitivity of 13C detection and the need for radiofrequency transmission at the 1H frequency while receiving the 13C signal, the latter requiring electrical decoupling of the 13C and 1H radiofrequency channels. In this study, we added traps to the 13C coil to construct a quadrature-13C/quadrature-1H surface coil, with sufficient isolation between channels to allow simultaneous operation at both frequencies without compromise in coil performance. Methods Isolation between channels was evaluated on the bench by measuring all coupling parameters. The quadrature mode of the quadrature-13C coil was assessed using in vitro 23Na gradient echo images. The signal-to-noise ratio (SNR) was measured on the glycogen and glucose resonances by 13C-MRS in vitro, compared with that obtained with a linear-13C/quadrature-1H coil, and validated by 13C-MRS in vivo in the human calf at 7T. Results Isolation between channels was better than −30 dB. The 23Na gradient echo images indicate a region where the field is strongly circularly polarized. The quadrature coil provided an SNR enhancement over a linear coil of 1.4, in vitro and in vivo. Conclusion It is feasible to construct a double-quadrature 13C-1H surface coil for proton decoupled sensitivity enhanced 13C-NMR spectroscopy in humans at 7T.
000197243 6531_ $$aCIBM-AIT
000197243 700__ $$0243736$$g144083$$aSerés Roig, Eulalia
000197243 700__ $$0243729$$g181986$$aMagill, Arthur W.
000197243 700__ $$0247900$$g185850$$aDonati, Guillaume
000197243 700__ $$aMeyerspeer, Martin
000197243 700__ $$0243883$$g169484$$aXin, Lijing
000197243 700__ $$aIpek, Ozlem$$g231389$$0247043
000197243 700__ $$aGruetter, Rolf$$g161735$$0243712
000197243 773__ $$j73$$tMagnetic Resonance in Medicine$$k2$$q894-900
000197243 8564_ $$uhttps://infoscience.epfl.ch/record/197243/files/Eulalia_MRM_2015.pdf$$zPublisher's version$$s369402$$yPublisher's version
000197243 909C0 $$xU10984$$0252276$$pLIFMET
000197243 909C0 $$pCIBM$$xU12623$$0252477
000197243 909CO $$qGLOBAL_SET$$pSB$$particle$$ooai:infoscience.tind.io:197243
000197243 917Z8 $$x161735
000197243 917Z8 $$x144083
000197243 917Z8 $$x161735
000197243 917Z8 $$x161735
000197243 937__ $$aEPFL-ARTICLE-197243
000197243 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000197243 980__ $$aARTICLE