000195777 001__ 195777
000195777 005__ 20181203023414.0
000195777 022__ $$a1749-5016
000195777 0247_ $$2doi$$a10.1093/scan/nst185
000195777 037__ $$aARTICLE
000195777 245__ $$aThe Brain Network reflecting Bodily Self-Consciousness: a functional connectivity study
000195777 269__ $$a2014
000195777 260__ $$bOxford Univ Press$$c2014$$aOxford
000195777 300__ $$a10
000195777 336__ $$aJournal Articles
000195777 520__ $$aSeveral brain regions are important for processing self-location and first-person perspective, two important aspects of bodily self-consciousness. However, the interplay between these regions has not been clarified. In addition, while self-location and first-person perspective in healthy subjects are associated with bilateral activity in temporo-parietal junction (TPJ), disturbed self-location and first-person perspective result from damage of only the bright TPJ. Identifying the involved brain network and understanding the role of hemispheric specializations in encoding self-location and first-person perspective, will provide important information on system-level interactions neurally mediating bodily self-consciousness. Here, we used functional connectivity and showed that right and left TPJ are bilaterally connected to supplementary motor area, ventral premotor cortex, insula, intraparietal sulcus, and occipito-temporal cortex. Furthermore, the functional connectivity between right TPJ and right insula had the highest selectivity for changes in self-location and first-person perspective. Finally, functional connectivity revealed hemispheric differences showing that self-location and first-person perspective modulated the connectivity between right TPJ, right posterior insula, and right supplementary motor area, and between left TPJ and right anterior insula. The present data extend previous evidence on healthy populations and clinical observations in neurological deficits, supporting a bilateral, but right-hemispheric dominant, network for bodily self-consciousness.
000195777 6531_ $$aself-location
000195777 6531_ $$afirst-person perspective
000195777 6531_ $$atemporoparietal junction
000195777 6531_ $$ainsula
000195777 6531_ $$amultisensory integration
000195777 700__ $$uEcole Polytech Fed Lausanne, Sch Life Sci, Ctr Neuroprosthet, CH-1015 Lausanne, Switzerland$$aIonta, Silvio
000195777 700__ $$0244850$$g158972$$uEcole Polytech Fed Lausanne, Sch Life Sci, Ctr Neuroprosthet, CH-1015 Lausanne, Switzerland$$aMartuzzi, Roberto
000195777 700__ $$0245162$$g209116$$uEcole Polytech Fed Lausanne, Sch Life Sci, Ctr Neuroprosthet, CH-1015 Lausanne, Switzerland$$aSalomon, Roy
000195777 700__ $$aBlanke, Olaf$$0240593$$g165806$$uEcole Polytech Fed Lausanne, Sch Life Sci, Ctr Neuroprosthet, CH-1015 Lausanne, Switzerland
000195777 773__ $$j9$$tSocial Cognitive And Affective Neuroscience$$k12$$q1904-1913
000195777 909C0 $$xU12599$$0252517$$pCNP
000195777 909C0 $$xU11025$$0252325$$pLNCO
000195777 909CO $$pSV$$particle$$ooai:infoscience.tind.io:195777
000195777 917Z8 $$x198754
000195777 917Z8 $$x146265
000195777 937__ $$aEPFL-ARTICLE-195777
000195777 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000195777 980__ $$aARTICLE