Client + cloud computing is a disruptive, new computing platform, combining diverse client devices -- PCs, smartphones, sensors, and single-function and embedded devices -- with the unlimited, on-demand computation and data storage offered by cloud computing services such as Amazon's AWS or Microsoft's Windows Azure. As with every advance in computing, programming is a fundamental challenge as client + cloud computing combines many difficult aspects of software development. Systems built for this world are inherently parallel and distributed, run on unreliable hardware, and must be continually available -- a challenging programming model for even the most skilled programmers. How then do ordinary programmers develop software for the Cloud? This talk presents one answer, Orleans, a software framework for building client + cloud applications. Orleans encourages use of simple concurrency patterns that are easy to understand and implement correctly, building on an actor-like model with declarative specification of persistence, replication, and consistency and using lightweight transactions to support the development of reliable and scalable client + cloud software.