000190949 001__ 190949
000190949 005__ 20190415234914.0
000190949 020__ $$a978-0-8243-3515-1
000190949 0247_ $$2doi$$a10.1146/annurev-bioeng-071812-152356
000190949 022__ $$a1523-9829
000190949 02470 $$2ISI$$a000323896000018
000190949 037__ $$aBOOK_CHAP
000190949 245__ $$aExploring Neural Cell Dynamics with Digital Holographic Microscopy
000190949 269__ $$a2013
000190949 260__ $$bAnnual Reviews$$c2013$$aPalo Alto
000190949 300__ $$a25
000190949 336__ $$aBook Chapters
000190949 490__ $$aAnnual Review of Biomedical Engineering
000190949 520__ $$aIn this review, we summarize how the new concept of digital optics applied to the field of holographic microscopy has allowed the development of a reliable and flexible digital holographic quantitative phase microscopy (DH-QPM) technique at the nanoscale particularly suitable for cell imaging. Particular emphasis is placed on the original biological information provided by the quantitative phase signal. We present the most relevant DH-QPM applications in the field of cell biology, including automated cell counts, recognition, classification, three-dimensional tracking, discrimination between physiological and pathophysiological states, and the study of cell membrane fluctuations at the nanoscale. In the last part, original results show how DH-QPM can address two important issues in the field of neurobiology, namely, multiple-site optical recording of neuronal activity and noninvasive visualization of dendritic spine dynamics resulting from a full digital holographic microscopy tomographic approach.
000190949 6531_ $$adigital holographic microscopy
000190949 6531_ $$adiffraction tomography
000190949 6531_ $$aquantitative phase microscopy
000190949 6531_ $$acell imaging
000190949 6531_ $$aneuronal activities
000190949 6531_ $$adendritic spines
000190949 700__ $$uCHUV, Dept Psychiat, Ctr Neurosci Psychiat, CH-1008 Prilly, Switzerland$$aMarquet, P.
000190949 700__ $$0240009$$g104931$$uEcole Polytech Fed Lausanne, Inst Microengn, CH-1015 Lausanne, Switzerland$$aDepeursinge, C.
000190949 700__ $$0243698$$g134990$$uCHUV, Dept Psychiat, Ctr Neurosci Psychiat, CH-1008 Prilly, Switzerland$$aMagistretti, P. J.
000190949 720_1 $$aYarmush, Ml$$eed.
000190949 773__ $$j15$$tAnnual Review Of Biomedical Engineering, Vol 15$$q407-431
000190949 909C0 $$xU11150$$0252265$$pLNDC
000190949 909C0 $$pLOA$$xU10346$$0252008
000190949 909CO $$pSTI$$pbook$$pchapter$$ooai:infoscience.tind.io:190949$$qSV
000190949 917Z8 $$x219572
000190949 937__ $$aEPFL-CHAPTER-190949
000190949 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000190949 980__ $$aCHAPTER