A Configurable IC to Control, Readout and Calibrate an Array of Biosensors

We present a novel integrated circuit for a biosensing data acquisition chain. The circuit controls and reads out five bimolecular sensors as well as pH and temperature sensors for biosensor calibration. The IC supports both <i>chronoamperometry</i> (CA) and <i>cyclic voltammetry</i> (CV) measurements, which are commonly used in biosensing. Different voltage waveforms are generated to control CV by using a single configurable waveform generator and programmable constant voltage levels are produced to enable CA. To reduce the area and power consumption of the interface electronics, a unified circuit is designed for CV, CA and pH readout. The biosensors produce currents that are converted by a 13.5-bit sigma delta analog to digital converter. The circuit has been designed and realized in 0.18 μm technology. It consumes 711 μW from a 1.8 V supply voltage, making it suitable for remotely powered and implantable applications.

Published in:
Proceedings of the 2013 European Conference on Circuit Theory and Design (ECCTD)
Presented at:
2013 European Conference on Circuit Theory and Design (ECCTD), Dresden, Germany, September 8-12, 2013

 Record created 2013-12-05, last modified 2019-03-16

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