We present a single-photon camera for fluorescence imaging capable of providing both intensity and images, with an accuracy better than 100ps; the camera was fabricated in standard CMOS technology. As a first step towards the study of biologically relevant samples, it was used to characterize in-vitro cultured melanoma cells labeled with indocyanine green (ICG) and ICG conjugated with cyclic pentapeptide (RGDfK). The application field would be fluorescence-guided surgical oncology.
Titre
Compact imaging system with single-photon sensitivity and picosecond time resolution for fluorescence-guided surgery with lifetime imaging capability
Publié dans
Clinical And Biomedical Spectroscopy And Imaging Iii
Pagination
7
Série
Proceedings of SPIE
Volume
8798
Présenté à
Conference on Clinical and Biomedical Spectroscopy and Imaging III, Munich, GERMANY, MAY 13-16, 2013
Date
2013
Editeur
Bellingham, Spie-Int Soc Optical Engineering
ISSN
0277-786X
ISBN
978-0-8194-9647-8
Date de création de la notice
2013-10-01