Organometallic anticancer agents that interfere with cellular energy processes: a subtle approach to inducing cancer cell death

Two hybrid compounds comprising an antimetastatic rutheniumarene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including highly relevant human glioblastoma cells, with an apparent synergistic action between the two components observed.


Publié dans:
Dalton Transactions, 42, 2347-2350
Année
2013
Publisher:
Cambridge, Royal Society of Chemistry
ISSN:
1477-9226
Laboratoires:




 Notice créée le 2013-03-26, modifiée le 2018-09-13


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