Organometallic anticancer agents that interfere with cellular energy processes: a subtle approach to inducing cancer cell death

Two hybrid compounds comprising an antimetastatic rutheniumarene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including highly relevant human glioblastoma cells, with an apparent synergistic action between the two components observed.


Published in:
Dalton Transactions, 42, 2347-2350
Year:
2013
Publisher:
Cambridge, Royal Society of Chemistry
ISSN:
1477-9226
Laboratories:




 Record created 2013-03-26, last modified 2018-03-17


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)