Microfluidic Synthesis of Cell-Type-Specific Artificial Extracellular Matrix Hydrogels
Allazetta, Simone; Hausherr, Tanja Cloé; Lutolf, Matthias
2013

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Abstract

Droplet microfluidic technology is applied for the high-throughput synthesis via Michael-type addition of reactive, micrometer-sized poly(ethylene glycol) (PEG) hydrogels (“microgels”) with precisely controlled dimension and physicochemical properties. A versatile chemical scheme is used to modify the reactive PEG microgels with tethered biomolecules to tune their bioactive properties for the bioreactor culture and manipulation of various (stem) cell types.

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Title Microfluidic Synthesis of Cell-Type-Specific Artificial Extracellular Matrix Hydrogels
Author(s) Allazetta, Simone ; Hausherr, Tanja Cloé ; Lutolf, Matthias
Published in Biomacromolecules
Pagination 10
Volume 14
Issue 4
Pages 1122-1131
Date 2013
ISSN 1525-7797
DOI https://doi.org/10.1021/bm4000162
Other identifier(s) View record in Web of Science
DOI: https://doi.org/10.1021/bm4000162
Laboratories UPLUT
Record Appears in Scientific production and competences > SV - School of Life Sciences > IBI-SV - Interfaculty Institute of Bioengineering > UPLUT - Prof. Lutolf Group
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2013-03-22

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