Remote System for Monitoring Animal Models With Single-Metabolite Bio-Nano-Sensors

A novel system for remote monitoring of metabolism in an animal model is proposed in this paper. The system is obtained by integrating bio-nano-sensors to detect single- metabolites, an electrochemical front-end made with off-the-shelf components, a radio frequency communication sub-system, and an antenna of new design. The system has been calibrated and tested for continuous monitoring of four different metabolites: glucose, lactate, glutamate, and adenosine triphosphate. Tests using animal models (mice) have been conducted to investigate tissue inflammation induced by the implanted bio-nano-sensors. These tests confirm that our system is suitable and reliable for remote monitoring of single-metabolites in experiments with animal models.


Published in:
IEEE Sensors Journal, 13, 3, 1018 - 1024
Year:
2013
Publisher:
Piscataway, Institute of Electrical and Electronics Engineers
ISSN:
1530-437X
Keywords:
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 Record created 2013-03-05, last modified 2018-12-03

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