Droplet-based Liquid-Liquid Extraction and On-Chip IR-Waveguide-Spectroscopy Detection of Cocaine in Human Saliva

We present a portable microsystem to quantitatively detect cocaine in human saliva. The chip combines a simple microfluidic method for multiphase liquid-liquid extraction to transfer cocaine from IR-light absorbing saliva to an IRtransparent solvent with the on-chip cocaine detection by IR-waveguide-spectroscopy (QC-laser, waveguide, detector). With our droplet-based extraction method we achieve an additional analyte pre-concentration of at least two orders of magnitude.


Presented at:
16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Okinawa, Japan, October 28-November 1, 2012
Year:
2012
Keywords:
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 Record created 2013-01-31, last modified 2018-03-18

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