Copper-catalyzed coupling of ortho-aminophenylboronic acid pinacol esters with β-ketoesters afforded, under mild base-free oxidative conditions, 2,3-disubstituted indoles featuring a key Chan-Lam type carbon-carbon bond forming reaction.
Title
Synthesis of Indoles by Copper-Catalyzed Heteroannulation of o-Aminophenylboronic Acid Pinacol Esters with β-Keto Esters
Published in
Synthesis
Pagination
4
Volume
44
Issue
24
Pages
3811-3814
Date
2012
Publisher
Stuttgart, Georg Thieme Verlag Kg
ISSN
1437-210X
Record creation date
2012-12-09