000181429 001__ 181429
000181429 005__ 20180317093005.0
000181429 0247_ $$2doi$$a10.1016/j.psychres.2012.07.001
000181429 022__ $$a0165-1781
000181429 02470 $$2ISI$$a000313764700091
000181429 037__ $$aARTICLE
000181429 245__ $$aCognitive disorganisation in schizotypy is associated with deterioration in visual backward masking
000181429 260__ $$aClare$$bElsevier$$c2012
000181429 269__ $$a2012
000181429 300__ $$a8
000181429 336__ $$aJournal Articles
000181429 520__ $$aTo understand the causes of schizophrenia, a search for stable markers (endophenotypes) is ongoing. In previous years, we have shown that the shine-through visual backward masking paradigm meets the most important characteristics of an endophenotype. Here, we tested masking performance differences between healthy students with low and high schizotypy scores as determined by the self-report O-Life questionnaire assessing schizotypy along three dimensions, i.e. positive schizotypy (unusual experiences), cognitive disorganisation, and negative schizotypy (introvertive anhedonia). Forty participants performed the shine-through backward masking task and a classical cognitive test, the Wisconsin Card Sorting Task (WCST). We found that visual backward masking was impaired for students scoring high as compared to low on the cognitive disorganisation dimension, whereas the positive and negative schizotypy dimensions showed no link to masking performance. We also found group differences for students scoring high and low on the cognitive disorganisation factor for the WCST. These findings indicate that the shine-through paradigm is sensitive to differences in schizotypy which are closely linked with the pathological expression in schizophrenia. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
000181429 6531_ $$aLow-level visual perception
000181429 6531_ $$aHigh risk studies
000181429 6531_ $$aEndophenotype
000181429 6531_ $$aDimensional and categorical models of schizotypy
000181429 6531_ $$aWCST
000181429 700__ $$0245151$$aCappe, Céline$$g209459
000181429 700__ $$0243629$$aHerzog, Michael H.$$g164642
000181429 700__ $$aHerzig, Daniela A.
000181429 700__ $$aBrand, Andreas
000181429 700__ $$aMohr, Christine
000181429 773__ $$j200$$q652-659$$tPsychiatry Research
000181429 909CO $$ooai:infoscience.tind.io:181429$$particle$$pSV
000181429 909C0 $$0252249$$pLPSY$$xU10987
000181429 917Z8 $$x166039
000181429 917Z8 $$x166039
000181429 917Z8 $$x166039
000181429 937__ $$aEPFL-ARTICLE-181429
000181429 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000181429 980__ $$aARTICLE