Ultrasensititve system for the real time detection of H2O2 based on strong coupling in a bio-plasmonic system

We theoretically investigate the dependence of the different parameters of an optical biosensor for the detection of Hydrogen peroxide (H2O2) based on absorption enhancement of Cytochrome c molecules near gold nanoparticles. H2O2 is a major reactive oxygen species which is involved in signaling pathways and oxidative stress in cells. We use the Green's function approach as well as confirm the corresponding simulation results using the surface integral formulation. Further we show that this technique can be applied for detection of other small molecules, like oxygen and carbon monoxide.


Published in:
Plasmonics In Biology And Medicine Ix, 8234, -
Presented at:
Conference on Plasmonics in Biology and Medicine IX, San Francisco, CA, Jan 22-24, 2012
Year:
2012
Publisher:
Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa
ISBN:
978-0-8194-8877-0
Keywords:
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 Record created 2012-07-27, last modified 2018-03-17

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