In Vitro Activities of the New Antitubercular Agents PA-824 and BTZ043 against Nocardia brasiliensis
Vera-Cabrera, Lucio; Campos-Rivera, Mayra Paola; Gonzalez-Martinez, Norma Alejandra; Ocampo-Candiani, Jorge; Cole, Stewart T.
2012

Abstract

The in vitro activity of PA-824 and BTZ043 against 30 Nocardia brasiliensis isolates was tested. The MIC50 and MIC90 values for PA-824 were both > 64 mu g/ml. The same values for BTZ043 were 0.125 and 0.250 mu g/ml. Given the MIC values for benzothiazinone (BTZ) compounds, we consider them good candidates to be tested in vivo against N. brasiliensis.

Details

Title In Vitro Activities of the New Antitubercular Agents PA-824 and BTZ043 against Nocardia brasiliensis
Author(s) Vera-Cabrera, Lucio ; Campos-Rivera, Mayra Paola ; Gonzalez-Martinez, Norma Alejandra ; Ocampo-Candiani, Jorge ; Cole, Stewart T.
Published in Antimicrobial Agents And Chemotherapy
Volume 56
Pages 3984-3985
Date 2012
Keywords
DOI https://doi.org/10.1128/AAC.00115-12
Other identifier(s) View record in Web of Science
Laboratories UPCOL
Record Appears in Scientific production and competences > SV - School of Life Sciences > SV Archives > UPCOL - Prof. Cole Group
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2012-07-20

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