In Vitro Activities of the New Antitubercular Agents PA-824 and BTZ043 against Nocardia brasiliensis

The in vitro activity of PA-824 and BTZ043 against 30 Nocardia brasiliensis isolates was tested. The MIC50 and MIC90 values for PA-824 were both > 64 mu g/ml. The same values for BTZ043 were 0.125 and 0.250 mu g/ml. Given the MIC values for benzothiazinone (BTZ) compounds, we consider them good candidates to be tested in vivo against N. brasiliensis.


Published in:
Antimicrobial Agents And Chemotherapy, 56, 3984-3985
Year:
2012
Keywords:
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 Record created 2012-07-20, last modified 2018-03-17


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