000180154 001__ 180154
000180154 005__ 20180913061445.0
000180154 0247_ $$2doi$$a10.1093/cercor/bhr226
000180154 02470 $$2ISI$$a000305610700009
000180154 037__ $$aARTICLE
000180154 245__ $$aWhite-Matter Connectivity between Face-Responsive Regions in the Human Brain
000180154 269__ $$a2012
000180154 260__ $$c2012
000180154 336__ $$aJournal Articles
000180154 520__ $$aFace recognition is of major social importance and involves highly selective brain regions thought to be organized in a distributed functional network. However, the exact architecture of interconnections between these regions remains unknown. We used functional magnetic resonance imaging to identify face-responsive regions in 22 participants and then employed diffusion tensor imaging with probabilistic tractography to establish the white-matter pathways between these functionally defined regions. We identified strong white-matter connections between the occipital face area (OFA) and fusiform face area (FFA), with a significant right-hemisphere predominance. We found no evidence for direct anatomical connections between FFA and superior temporal sulcus (STS) or between OFA and STS, contrary to predictions based on current cognitive models. Instead, our findings point to segregated processing along a ventral extrastriate visual pathway to OFA-FFA and another more dorsal system connected to STS and frontoparietal areas. In addition, early occipital areas were found to have direct connections to the amygdala, which might underlie a rapid recruitment of limbic brain areas by visual inputs bypassing more elaborate extrastriate cortical processing. These results unveil the structural neural architecture of the human face recognition system and provide new insights on how distributed face-responsive areas may work together.
000180154 6531_ $$aDTI
000180154 6531_ $$aface network
000180154 6531_ $$aface processing
000180154 6531_ $$afMRI
000180154 6531_ $$atractography
000180154 6531_ $$awhite-matter connectivity
000180154 6531_ $$aSuperior Temporal Sulcus
000180154 6531_ $$aProbabilistic Diffusion Tractography
000180154 6531_ $$aPosterior Parietal Cortex
000180154 6531_ $$aHuman Extrastriate Cortex
000180154 6531_ $$aVentral Visual Stream
000180154 6531_ $$aHuman Neural System
000180154 6531_ $$aEvent-Related Fmri
000180154 6531_ $$aRhesus-Monkey
000180154 6531_ $$aIn-Vivo
000180154 6531_ $$aFusiform Cortex
000180154 700__ $$aGschwind, Markus
000180154 700__ $$aPourtois, Gilles
000180154 700__ $$aSchwartz, Sophie
000180154 700__ $$0240173$$aVan de Ville, Dimitri$$g152027
000180154 700__ $$aVuilleumier, Patrik
000180154 773__ $$j22$$k7$$q1564-1576$$tCerebral Cortex
000180154 909C0 $$0252169$$pMIPLAB$$xU12143
000180154 909CO $$ooai:infoscience.tind.io:180154$$pSTI$$particle
000180154 917Z8 $$x152027
000180154 917Z8 $$x148230
000180154 937__ $$aEPFL-ARTICLE-180154
000180154 973__ $$aOTHER$$rREVIEWED$$sPUBLISHED
000180154 980__ $$aARTICLE