Oligonucleotide Delivery by Cell-Penetrating "Striped" Nanoparticles
Gold nanoparticles coated with homogeneous (MUS) or "striped" (MUS-OT) ligand shells can be conjugated with double or single stranded DNA, and particles with either ligand configuration effectively carry DNA into melanoma tumor cells. When endocytosis is inhibited, however, MUS-OT particles continue to mediate DNA delivery, while the delivery ability of MUS particles is abolished. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Jewell, C. M., Jung, J.-M., Atukorale, P. U., Carney, R. P., Stellacci, F., & Irvine, D. J. (2011). Oligonucleotide Delivery by Cell-Penetrating “Striped” Nanoparticles. Angewandte Chemie International Edition, 50, 12312–12315. https://doi.org/10.1002/anie.201104514
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WOS:000298088600037
2011
50
12312
12315
REVIEWED
EPFL