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Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons
Yang, Bin
;
Sun, Xiaqin
;
Lashuel, Hilal
;
Zhang, Yan
2012
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Abstract
To investigate whether intracellular amyloid beta (iA beta) induces toxicity in wild type (WT) and APP/PS1 mice, a mouse model of Alzheimer's disease.
Details
Title
Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons
Author(s)
Yang, Bin
;
Sun, Xiaqin
;
Lashuel, Hilal
;
Zhang, Yan
Published in
Neuroscience Bulletin
Volume
28
Pages
233-239
Date
2012
Keywords
amyloid
;
reactive oxidative species
;
App/ Ps1
;
aggregation
;
toxicity
;
Alzheimers-Disease
;
Transgenic Mice
;
Beta-Peptide
;
A-Beta-42 Accumulation
;
Precursor Protein
;
Plaque-Formation
;
Stress
;
Apoptosis
;
Pathology
;
Oligomers
DOI
https://doi.org/10.1007/s12264-012-1239-1
Other identifier(s)
View record in Web of Science
Laboratories
LMNN
Record Appears in
Scientific production and competences
>
SV - School of Life Sciences
>
BMI - Brain Mind Institute
>
LMNN - Laboratory of Molecular Neurobiology and Neuroproteomics
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2012-06-22
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