Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons

Yang, Bin; Sun, Xiaqin; Lashuel, Hilal; Zhang, Yan

doi:10.1007/s12264-012-1239-1

Yang, Bin; Sun, Xiaqin; Lashuel, Hilal; Zhang, Yan

2012

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Abstract

To investigate whether intracellular amyloid beta (iA beta) induces toxicity in wild type (WT) and APP/PS1 mice, a mouse model of Alzheimer's disease.

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Title Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons

Author(s) Yang, Bin ; Sun, Xiaqin ; Lashuel, Hilal ; Zhang, Yan

Published in Neuroscience Bulletin

Volume 28

Pages 233-239

Date 2012

Keywords

amyloid; reactive oxidative species; App/ Ps1; aggregation; toxicity; Alzheimers-Disease; Transgenic Mice; Beta-Peptide; A-Beta-42 Accumulation; Precursor Protein; Plaque-Formation; Stress; Apoptosis; Pathology; Oligomers

DOI https://doi.org/10.1007/s12264-012-1239-1

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Laboratories LMNN

Record Appears in Scientific production and competences > SV - School of Life Sciences > BMI - Brain Mind Institute > LMNN - Laboratory of Molecular Neurobiology and Neuroproteomics
Peer-reviewed publications
Work produced at EPFL
Journal Articles
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Record creation date 2012-06-22

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