An All-Digital, Time-gated 128x128 SPAD Array for On-chip, Filter-less Fluorescence Detection

This paper presents an on-chip, filter-less fluorescence detector using an all-digital, time-resolved imager based on a CMOS single-photon detector array with limited in situ processing. The device comprises an array of pixels capable of detecting single photons integrated with time gating circuitry and a 1-bit memory. The sensor allows on-chip, filter-less fluorescence detection and fluorescence lifetime imaging microscopy (FLIM) for micro total analysis systems (μ-TAS) and point-of-care testing (POCT) applications. The sensor was tested as an on-chip optical DNA detector using Cy5 labeled DNA molecules directly placed on the sensor surface.


Published in:
Proc. IEEE Transducers
Presented at:
IEEE Transducers, June, 2011
Year:
2011
Laboratories:




 Record created 2012-06-12, last modified 2018-03-17

n/a:
Download fulltext
PDF

Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)