Enantioselective Rhodium(I)-Catalyzed [3+2] Annulations of Aromatic Ketimines Induced by Directed C?H Activations
Tran, Duc N.; Cramer, Nicolai
2011

Abstract

Triple selectivity: Highly substituted indenylamines can be obtained with high enantioselectivity by formal [3+2] additions of aryl ketimines with internal alkynes. These rhodium(I)-catalyzed processes proceed by selective C-H activation of one of the two arene substituents, regioselective carbometalation of the alkyne, and enantioselective addition across the imine. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Details

Title Enantioselective Rhodium(I)-Catalyzed [3+2] Annulations of Aromatic Ketimines Induced by Directed C?H Activations
Author(s) Tran, Duc N. ; Cramer, Nicolai
Published in Angewandte Chemie-International Edition
Volume 50
Pages 11098-11102
Date 2011
Keywords
DOI https://doi.org/10.1002/anie.201105766
Other identifier(s) View record in Web of Science
Laboratories LCSA
Record Appears in Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LCSA - Laboratory of Asymmetric Catalysis and Synthesis
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2012-06-12

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