Nanomechanics of Streptavidin Hubs for Molecular Materials

A new strategy is reported for creating protein-based nanomaterials by genetically fusing large polypeptides to monomeric streptavidin and exploiting the propensity of streptavidin monomers(SM) to self-assemble into stable tetramers. We have characterized the mechanical properties of streptavidin-linked structures and measured, for the first time, the mechanical strength of streptavidin tetramers themselves. Using streptavidin tetramers as molecular hubs offers a unique opportunity to create a variety of well-defined, self-assembled protein-based (nano) materials with unusual mechanical properties.


Published in:
Advanced Materials, 23, 5684-+
Year:
2011
Keywords:
Laboratories:




 Record created 2012-06-12, last modified 2018-03-17


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