68Ga-NODAGA-RGDyK for αvβ3 integrin PET imaging. Preclinical investigation and dosimetry

Buchegger, F.; Viertl, D.; Baechler, S.; Dunet, V.; Kosinski, M.; Poitry-Yamate, C.; Rüegg, C.; Prior, J. O.

doi:10.3413/Nukmed-0416-11-06

Buchegger, F.; Viertl, D.; Baechler, S.; Dunet, V.; Kosinski, M.; Poitry-Yamate, C.; Rüegg, C.; Prior, J. O.

2011

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Abstract

To visualize neovasculature and/or tumour integrin αvβ3 we selected the binding moiety Arg-Gly-Asp-D-Tyr-Lys (RGDyK) coupled to NODAGA for labeling with 68Ga.

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Title 68Ga-NODAGA-RGDyK for αvβ3 integrin PET imaging. Preclinical investigation and dosimetry

Author(s) Buchegger, F. ; Viertl, D. ; Baechler, S. ; Dunet, V. ; Kosinski, M. ; Poitry-Yamate, C. ; Rüegg, C. ; Prior, J. O.

Published in Nuklearmedizin. Nuclear medicine

Volume 50

Issue 6

Pages 225-33

Date 2011

Publisher Schattauer

ISSN 0029-5566

Keywords

Integrin; alpha(v)beta(3); RGD-peptide; cyclic RGDyK; Ga-68-NODAGA-RGDyK; PET imaging; Personal-Computer Software; Internal Dose Assessment; Rgd Peptides; Nuclear-Medicine; Structural Basis; Expression; F-18-Galacto-Rgd; Biodistribution; Proliferation; Micropet; CIBM-PET

DOI https://doi.org/10.3413/Nukmed-0416-11-06

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Laboratories LIFMET
CIBM

Record Appears in Scientific production and competences > SB - School of Basic Sciences > IPHYS - Institute of Physics > LIFMET - Laboratory of functional and metabolic imaging
Scientific production and competences > SB - School of Basic Sciences > CIBM - Biomedical Imaging Research Center
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Work produced at EPFL
Journal Articles
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Record creation date 2012-05-26

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