000176809 001__ 176809
000176809 005__ 20180913061239.0
000176809 0247_ $$2doi$$a10.1039/c2dt30388d
000176809 022__ $$a1477-9226
000176809 02470 $$2ISI$$a000302737600007
000176809 037__ $$aARTICLE
000176809 245__ $$aGold nanoparticles functionalised with stable, fast water exchanging Gd3+ chelates as high relaxivity contrast agents for MRI
000176809 260__ $$bRoyal Society of Chemistry$$c2012
000176809 269__ $$a2012
000176809 336__ $$aJournal Articles
000176809 520__ $$aGold nanoparticles functionalized with Gd3+ chelates displaying fast water exchange, superb pH stability and inertness towards transmetalation with Zn2+ have been prepared and characterized as a new high relaxivity (29 mM(-1) s(-1), 30 MHz, 25 degrees C) contrast agent potentially safe for in vivo MRI applications. The Lipari-Szabo treatment for internal rotation was used to evaluate the effect of linker flexibility on the relaxivity of the gold nanoparticles. The effect of fast water exchange on the relaxivity of gold nanoparticles functionalized with Gd3+ chelates is also addressed in this communication.
000176809 6531_ $$aComplexes
000176809 700__ $$aFerreira, M. F.
000176809 700__ $$0242517$$aMousavi, B.$$g183938
000176809 700__ $$aFerreira, P. M.
000176809 700__ $$aMartins, C. I. O.
000176809 700__ $$0240250$$aHelm, L.$$g144957
000176809 700__ $$aMartins, J. A.
000176809 700__ $$aGeraldes, C. F. G. C.
000176809 773__ $$j41$$q5472-5475$$tDalton Transactions
000176809 8564_ $$s178606$$uhttps://infoscience.epfl.ch/record/176809/files/JCSDalton12-5472.pdf$$yn/a$$zn/a
000176809 909C0 $$0252059$$pLCIB$$xU10103
000176809 909CO $$ooai:infoscience.tind.io:176809$$pSB$$particle
000176809 917Z8 $$x144957
000176809 937__ $$aEPFL-ARTICLE-176809
000176809 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000176809 980__ $$aARTICLE