Early Cell Death Detection with Digital Holographic Microscopy

Background: Digital holography provides a non-invasive measurement of the quantitative phase shifts induced by cells in culture, which can be related to cell volume changes. It has been shown previously that regulation of cell volume, in particular as it relates to ionic homeostasis, is crucially involved in the activation/inactivation of the cell death processes. We thus present here an application of digital holographic microscopy (DHM) dedicated to early and label-free detection of cell death.


Published in:
Plos One, 7, 1, e30912
Year:
2012
Publisher:
Public Library of Science
ISSN:
1932-6203
Keywords:
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 Record created 2012-04-19, last modified 2018-03-18

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